Study on the Immune Activity of Mice In Vitro and In Vivo with Nano-Material Adjuvant

This paper investigates the effects of graphene quantum dots and mesoporous silica as nanomaterial adjuvants on immune activity in mice both in vitro and in vivo. The two materials have distinct properties; graphene quantum dots possess unique optical and electrical characteristics, while mesoporous silica features a regular pore structure. In vitro experiments show differences in their effects on immune cell activation and cytokine secretion; in vivo experiments reveal varying performances in antibody production and immune cell function regulation. Their mechanisms of action and safety profiles also differ, offering distinct advantages in application prospects. These two nanomaterial adjuvants provide new directions for the development of immunology, warranting further exploration.

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Publication Details

Journal
Journal of Clinical and Nursing Research
Published
2025-05-06
DOI
https://doi.org/10.26689/jcnr.v9i4.10485
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
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article

Study on the Immune Activity of Mice In Vitro and In Vivo with Nano-Material Adjuvant

Qiran Wang
Journal of Clinical and Nursing Research
Nanoparticle-Based Drug Delivery
article

Study on the Immune Activity of Mice In Vitro and In Vivo with Nano-Material Adjuvant

Qiran Wang
article en

Abstract

This paper investigates the effects of graphene quantum dots and mesoporous silica as nanomaterial adjuvants on immune activity in mice both in vitro and in vivo. The two materials have distinct properties; graphene quantum dots possess unique optical and electrical characteristics, while mesoporous silica features a regular pore structure. In vitro experiments show differences in their effects on immune cell activation and cytokine secretion; in vivo experiments reveal varying performances in antibody production and immune cell function regulation. Their mechanisms of action and safety profiles also differ, offering distinct advantages in application prospects. These two nanomaterial adjuvants provide new directions for the development of immunology, warranting further exploration.

Journal of Clinical and Nursing ResearchVol. 9(4)
Southwest Minzu University (CN)
Openalex Percentile: Top 94%
Nanoparticle-Based Drug Delivery
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Study on the Immune Activity of Mice In Vitro and In Vivo with Nano-Material Adjuvant — Qiran Wang · Journal of Clinical and Nursing Research (2025) | TGRS Research Map | TGRS