U-shaped association between myeloperoxidase levels and anxiety risk: a cross-sectional study in a Chinese population
Plasma MPO demonstrates a U-shaped association with anxiety risk independent of cardiometabolic confounders. Diabetic individuals exhibit heightened susceptibility to MPO-related anxiety, suggesting synergistic neuroinflammatory pathways. Monitoring MPO may aid in risk stratification and personalized interventions, particularly in populations with diabetes.
Authors
- Junteng Zhou (ORCID: https://orcid.org/0000-0002-4257-0488)
- Qi Kong (ORCID: https://orcid.org/0000-0002-7077-8905)
- Yan Huang (ORCID: https://orcid.org/0000-0002-2072-0190)
- Xiaojing Liu (ORCID: https://orcid.org/0000-0001-7932-1955)
Institutions
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-05-07
- DOI
- https://doi.org/10.3389/fpubh.2025.1596844
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58
Funders
- National Natural Science Foundation of China
- Sichuan University
- West China Hospital, Sichuan University