Circ_0081343 promotes autophagy and alleviates pyroptosis via PI3 K/AKT/HIF-1α axis in hypoxia-induced fetal growth restriction of mice
circ_0081343 alleviated gestational hypoxia-induced placental dysfunction and fetal growth restriction (FGR) by promoting autophagy and inhibiting pyroptosis, potentially through the PI3 K/AKT/HIF-1α pathway.
Authors
- Linmei Zheng (ORCID: https://orcid.org/0000-0002-5230-786X)
- Fang Jun-bo
- Fiaz Ahmad (ORCID: https://orcid.org/0000-0001-6179-3399)
- Rong Tang
- Lei Shi (ORCID: https://orcid.org/0000-0002-6631-6732)
- Jing Li (ORCID: https://orcid.org/0000-0001-7792-4322)
- Xiaoju Chen (ORCID: https://orcid.org/0000-0002-3579-0247)
Institutions
- Northwestern Polytechnical University (CN)
- Nanfang Hospital (CN)
- Hainan General Hospital (CN)
- Southern Medical University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Animal Cells and Systems
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1080/19768354.2025.2498932
- Citations
- 2
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Natural Science Foundation of Guangdong Province
- Natural Science Foundation of Hainan Province
- China International Medical Foundation