Endoplasmic reticulum protein 29 negatively regulates platelet functions and thrombosis in mice
ERp29 is the first disulfide isomerase without the CXYC motif that negatively regulates platelet function. This study provides new insight into the redox network controlling thrombosis.
Authors
- Yi Wu (ORCID: https://orcid.org/0000-0002-5116-9266)
- Chao Fang (ORCID: https://orcid.org/0000-0003-2524-3730)
- Keyu Lv (ORCID: https://orcid.org/0000-0001-6097-4593)
- Xiaofeng Yan (ORCID: https://orcid.org/0009-0001-3814-9957)
- Yishan Lu (ORCID: https://orcid.org/0000-0003-4770-4323)
- Miao Jiang (ORCID: https://orcid.org/0000-0002-4929-4885)
- Aizhen Yang (ORCID: https://orcid.org/0000-0002-8067-4771)
Institutions
- Soochow University (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Thrombosis Journal
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1186/s12959-025-00726-8
- Citations
- 3
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 3.45
Funders
- National Natural Science Foundation of China
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- State Key Laboratory of Radiation Medicine and Protection