Changes in brain function during negative emotion processing following cognitive–behavioural therapy in depressive disorders
Following CBT, reduced activity in emotion-processing regions was observed in patients with depressive disorders, with hippocampal activity decreases linked to treatment response. This suggests successful CBT could correct biased emotion processing, potentially by altering activity in key areas of emotion processing. Hippocampal activity may function as a predictive marker of CBT response.
Authors
- Ronny Redlich (ORCID: https://orcid.org/0000-0002-7018-4525)
- Janine Selle
- L. Fisch (ORCID: https://orcid.org/0000-0001-6424-7676)
- Elisabeth Johanna Leehr (ORCID: https://orcid.org/0000-0002-9264-5003)
- Melissa Klug (ORCID: https://orcid.org/0000-0002-2234-4096)
- Verena Enneking (ORCID: https://orcid.org/0000-0002-6547-0324)
- Esther Zwiky (ORCID: https://orcid.org/0000-0002-6733-8087)
- Tiana Borgers (ORCID: https://orcid.org/0000-0003-2309-6079)
- Nils Opel (ORCID: https://orcid.org/0000-0003-4749-3298)
- Konrad Schöniger (ORCID: https://orcid.org/0000-0002-1849-9490)
- Antonia Küttner (ORCID: https://orcid.org/0009-0001-6364-4896)
- Laura Neutz
- Philine König (ORCID: https://orcid.org/0000-0002-5410-5444)
- Udo Dannlowski
- Lydia Klein
Institutions
- University of Münster (DE)
- Jena University Hospital (DE)
- IntellADAPT (United States) (US)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1192/bjp.2025.71
- Citations
- 2
- Primary Topic
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Type
- article
- Field-Weighted Citation Impact
- 4.24
Funders
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung