Prognostic Factors for Gastroesophageal Varices After Endoscopic Treatment in Patients Without Advanced Hepatocellular Carcinoma

In our previous report, we identified advanced hepatocellular carcinoma as a prognostic factor for gastroesophageal varices following endoscopic treatment. In this study, we aimed to identify prognostic factors for gastroesophageal varices after endoscopic treatment in patients without advanced hepatocellular carcinoma. Kaplan–Meier and Cox proportional hazards models were used to determine the prognostic factors in 263 patients with chronic liver diseases without advanced hepatocellular carcinoma who underwent endoscopic therapy for gastroesophageal varices. After endoscopic treatment, the cumulative overall survival rates for gastroesophageal varices in patients without advanced hepatocellular carcinoma were 90.28%, 79.17%, and 69.56% at 1, 3, and 5 years, respectively. The prognostic factors associated with this treatment were age, etiology, and albumin-bilirubin grade. The presence of non-advanced hepatocellular carcinoma was not associated with prognosis. Managing hepatocellular carcinoma and maintaining sufficient liver function are crucial for long-term survival following endoscopic treatment for gastroesophageal varices.

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Journal
SN Comprehensive Clinical Medicine
Published
2025-05-07
DOI
https://doi.org/10.1007/s42399-025-01820-8
Primary Topic
Liver Disease and Transplantation
Type
article
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article

Prognostic Factors for Gastroesophageal Varices After Endoscopic Treatment in Patients Without Advanced Hepatocellular Carcinoma

Ikuya Sugiura, Shojiro Uozumi, Toshiyuki Baba, Hitoshi Yoshida
SN Comprehensive Clinical Medicine
Liver Disease and Transplantation
article

Prognostic Factors for Gastroesophageal Varices After Endoscopic Treatment in Patients Without Advanced Hepatocellular Carcinoma

Ikuya Sugiura, Shojiro Uozumi, Toshiyuki Baba, Hitoshi Yoshida
article en

Abstract

In our previous report, we identified advanced hepatocellular carcinoma as a prognostic factor for gastroesophageal varices following endoscopic treatment. In this study, we aimed to identify prognostic factors for gastroesophageal varices after endoscopic treatment in patients without advanced hepatocellular carcinoma. Kaplan–Meier and Cox proportional hazards models were used to determine the prognostic factors in 263 patients with chronic liver diseases without advanced hepatocellular carcinoma who underwent endoscopic therapy for gastroesophageal varices. After endoscopic treatment, the cumulative overall survival rates for gastroesophageal varices in patients without advanced hepatocellular carcinoma were 90.28%, 79.17%, and 69.56% at 1, 3, and 5 years, respectively. The prognostic factors associated with this treatment were age, etiology, and albumin-bilirubin grade. The presence of non-advanced hepatocellular carcinoma was not associated with prognosis. Managing hepatocellular carcinoma and maintaining sufficient liver function are crucial for long-term survival following endoscopic treatment for gastroesophageal varices.

SN Comprehensive Clinical MedicineVol. 7(1)
SHOWA Medical University (JP), SHOWA Medical University Northern Yokohama Hospital (JP)
Good health and well-being
Openalex Percentile: Top 86%
Liver Disease and Transplantation
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Prognostic Factors for Gastroesophageal Varices After Endoscopic Treatment in Patients Without Advanced Hepatocellular Carcinoma — Ikuya Sugiura, Shojiro Uozumi, et al. · SN Comprehensive Clinical Medicine (2025) | TGRS Research Map | TGRS