Retrospective study on the correlation between CXCL13, immune infiltration, and tertiary lymphoid structures in cutaneous squamous cell carcinoma
CXCL13 is up-regulated in cSCC, which shows a significant positive correlation with immune infiltration and TLS formation. Our results underscore the role of CXCL13 in shaping the cSCC microenvironment, highlighting its potential as a therapeutic target.
Authors
- Yeqiang Liu (ORCID: https://orcid.org/0000-0003-3758-1390)
- Guorong Yan (ORCID: https://orcid.org/0000-0001-9200-2959)
- Qingyu Zeng (ORCID: https://orcid.org/0000-0003-3170-7706)
- Yuhao Wu (ORCID: https://orcid.org/0000-0002-1799-4967)
- Yulu Chen (ORCID: https://orcid.org/0000-0003-2208-7242)
- Long Wen (ORCID: https://orcid.org/0000-0003-3871-9232)
- Guolong Zhang (ORCID: https://orcid.org/0000-0002-2724-8087)
- Zijun Zhao (ORCID: https://orcid.org/0000-0003-2844-9881)
- Mingshun Wu
- Dekun Song
Institutions
- Tongji University (CN)
- Shanghai Skin Disease Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-05-07
- DOI
- https://doi.org/10.7717/peerj.19398
- Citations
- 1
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China