Use of a sodium heparin gel in the rehabilitation of patients after cosmetic procedures

A water-soluble anticoagulant obtained about a century ago from animal tissues, heparin has since been used in the clinic for the prevention and treatment of thrombosis, including after surgical treatment, in cardiovascular and viral diseases. The main anticoagulant effect of heparin is best studied, it is based on a combined mechanism of interaction between an inhibitor of plasma serine proteinases, antithrombin and thrombin or factor Xa. According to its chemical structure, heparin is a heterogeneous, linear, highly sulfated anionic glycosaminoglycan with a wide range of relative molecular weight and charge density; these structural properties allow heparin to selectively interact with several proteins, which ensures its various pharmacological functions. Currently, 250 different proteins are known that bind to heparin and whose biological properties can be regulated by it. With the development of various directions in medicine, various properties of heparin have been revealed, which potentially have therapeutic value in other conditions with an inflammatory component. Heparin has a number of additional pharmacological activities, including antiviral, antitumor, anti-inflammatory, antihypolipidemic and antiangiogenic, which allows to expand the scope of its application. In particular, in dermatology and cosmetology, heparin has proven itself in the treatment of localized infiltrates, edema and subcutaneous hematomas. Various invasive and non-invasive procedures in cosmetology, especially in patients with undifferentiated connective tissue dysplasia, may be accompanied by edema, redness, and hematoma formation. Due to its anticoagulant, regenerative, decongestant, and anti-inflammatory properties, sodium heparin gel can shorten the rehabilitation period.