Molecular mechanisms of naringin's high lipid‐lowering activity: pancreatic lipase inhibition and fat accumulation reduction
Naringin effectively inhibits pancreatic lipase through competitive binding and structural modifications, reducing lipid digestion and absorption. The inhibitory effect of naringin on pancreatic lipase might provide new insights into the role of naringin in lipid metabolism regulation and potential application in obesity management. © 2025 Society of Chemical Industry.
Authors
- Ye Zhang (ORCID: https://orcid.org/0000-0002-6903-5602)
- Baorui Li
- Aizhen Zong (ORCID: https://orcid.org/0000-0003-4617-6995)
- Jing Wang (ORCID: https://orcid.org/0000-0003-2877-6516)
- Jiao Xie (ORCID: https://orcid.org/0000-0003-2857-3823)
- Wenjing Jiang (ORCID: https://orcid.org/0009-0009-9473-1042)
- Ningning Cheng
- Kai Yu
Institutions
- Tianjin University of Science and Technology (CN)
- Guiyang Medical University (CN)
- China Aerospace Science and Industry Corporation (China) (CN)
- Shandong Academy of Agricultural Sciences (CN)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1002/jsfa.14336
- Citations
- 1
- Primary Topic
- Phytochemical compounds biological activities
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province