Design of Experiments Assisted Formulation Optimization and Evaluation of Efavirenz Solid Dispersion Adsorbate for Improvement in Dissolution and Flow Properties

The findings of this study suggest that the SDA method is an effective approach for enhancing the dissolution and flow characteristics of EFZ and may serve as an alternative strategy for preparing solid dosage forms in commercial applications.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2025-05-01
DOI
https://doi.org/10.2147/dddt.s517021
Citations
1
Primary Topic
Analytical Chemistry and Chromatography
Type
article
Field-Weighted Citation Impact
0.76
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article

Design of Experiments Assisted Formulation Optimization and Evaluation of Efavirenz Solid Dispersion Adsorbate for Improvement in Dissolution and Flow Properties

Yahya Alhamhoom, Mohammad J. Akbar, Sandeep A Wathore, Purushottam Gangane et al.
1 citations
Drug Design Development and Therapy
Analytical Chemistry and Chromatography
0.76
article

Design of Experiments Assisted Formulation Optimization and Evaluation of Efavirenz Solid Dispersion Adsorbate for Improvement in Dissolution and Flow Properties

Yahya Alhamhoom, Mohammad J. Akbar, Sandeep A Wathore, Purushottam Gangane, Mohammed Kaleem, Md Ali Mujtaba, Md Abdur Rashid, Mohammad Khalid, Gamal Osman Elhassan, Mohini Janardan Jagtap
article en
1 citations

Abstract

The findings of this study suggest that the SDA method is an effective approach for enhancing the dissolution and flow characteristics of EFZ and may serve as an alternative strategy for preparing solid dosage forms in commercial applications.

Drug Design Development and TherapyVol. Volume 19
Northern Border University (SA), Rashtrasant Tukadoji Maharaj Nagpur University (IN), Prince Sattam Bin Abdulaziz University (SA), Qassim University (SA), Bombay College of Pharmacy (IN), Imam Abdulrahman Bin Faisal University (SA), King Khalid University (SA)
Openalex Percentile: Top 32%
Analytical Chemistry and Chromatography
0.76
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Design of Experiments Assisted Formulation Optimization and Evaluation of Efavirenz Solid Dispersion Adsorbate for Improvement in Dissolution and Flow Properties — Yahya Alhamhoom, Mohammad J. Akbar, et al. · Drug Design Development and Therapy (2025) | TGRS Research Map | TGRS