Adaptations and Heterogeneity of Treatment Effects in Platform Trials—Protocol for Two Methodological Studies
The two proposed methodological studies will provide an overview of important methodological features regarding the assessment of HTE and adaptations used in adaptive platform trials. Better knowledge of available methods to assess these features can improve the conditions for designing adaptive platform trials and identify areas for further development.
Authors
- Anders Perner (ORCID: https://orcid.org/0000-0002-4668-0123)
- Ewan C. Goligher (ORCID: https://orcid.org/0000-0002-0990-6701)
- Tine Sylvest Meyhoff (ORCID: https://orcid.org/0000-0002-1840-1596)
- Anders Granholm (ORCID: https://orcid.org/0000-0001-5799-7655)
- Aksel Karl Georg Jensen (ORCID: https://orcid.org/0000-0002-1459-0465)
- Marion Campbell (ORCID: https://orcid.org/0000-0001-5386-4097)
- Morten Hylander Møller
Institutions
- University of Copenhagen (DK)
- University of Toronto (CA)
- University of Aberdeen (GB)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- Acta Anaesthesiologica Scandinavica
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1111/aas.70044
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 0.00