Clinical characteristics of chronic heart failure depending on the severity of the domains of senile asthenia syndrome

BACKGROUND. Due tothe global increase in life extension and, as a result, the increase in the absolute number of older people suffering from chronic heart failure (CHF), it's becoming relevant to find a specific approach to their management. A special role in elderly patients with CHF may be played by the initial extracardial state of health, which consists of a combination of disorders in cognitive function, nutrition, social component and functional reserves. A large number of diagnostic methods for senile asthenia syndrome have been proposed, each of them has its advantages and limitations. However, there is currently no gold standard for the diagnosis of senile asthenia syndrome in patients with CHF. The Heart Failure Association of the European Society of Cardiology (HFA-ESC) proposed in 2019 a new definition of fragility with 4 domains―clinical, psycho-cognitive, functional, and social, however, their clinical and prognostic significance has not been fully determined.