Drain Fluid Amylase as an Early Negative Predictor of Salivary Fistula Following Free Flap Reconstruction
Change in surgical drain fluid amylase from postoperative day 1 to 2 was associated with fistula formation following free flap reconstruction of the aerodigestive tract. Importantly, a change in amylase of < 15% from postoperative day 1 to 2 was best at identifying patients who are at low risk of developing salivary fistula during postoperative hospitalization, with a negative predictive value of 91.5%.
Authors
- Kevin J. Contrera (ORCID: https://orcid.org/0000-0002-2570-1706)
- Mario G. Solari (ORCID: https://orcid.org/0000-0001-9366-521X)
- Mark Kubik (ORCID: https://orcid.org/0000-0002-8646-9920)
- Lauren Gardiner (ORCID: https://orcid.org/0000-0001-5595-4010)
- Shaum Sridharan (ORCID: https://orcid.org/0000-0001-6049-1508)
- Zoey Morton (ORCID: https://orcid.org/0000-0002-8188-7373)
- Matthew E. Spector (ORCID: https://orcid.org/0000-0001-7646-6075)
- Micah K. Harris (ORCID: https://orcid.org/0009-0004-5036-8919)
- Ore Odeniyi
Institutions
- University of Pittsburgh Medical Center (US)
Publication Details
- Journal
- Microsurgery
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1002/micr.70066
- Primary Topic
- Reconstructive Surgery and Microvascular Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00