Multisite Chronic Pain and the Risk of Breast Cancer and Its Subtypes: A Mendelian Randomization Study
Genetic evidence in this study suggests a causal link between stomach/abdominal pain and overall BC, and between neck/shoulder pain and Luminal-A BC risk in Europeans. Determining the cause of this discrepancy might shed light on the complicated link between breast cancer etiology and chronic pain genetics, emphasizing the need for further investigations and potential clinical applications to enhance breast cancer prevention and management.
Authors
- Jintao Liu (ORCID: https://orcid.org/0000-0002-2363-0748)
- Shuke Ge
- Rongdi Wang
- Yudong Hou (ORCID: https://orcid.org/0000-0002-0981-3572)
- Yanyan Song
- Min Zhang (ORCID: https://orcid.org/0000-0001-5750-4849)
- Teng Wang (ORCID: https://orcid.org/0000-0001-6092-9522)
- Meng Xu (ORCID: https://orcid.org/0000-0002-9470-9410)
- Wanyu Li (ORCID: https://orcid.org/0009-0007-7264-3370)
- Jianheng Bao
- Yaohua Shang
- Longbi Liu
Institutions
- Dalian Medical University (CN)
- Dalian Municipal Central Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/jpr.s489703
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16