Integrating local malaria molecular monitoring into regular malaria indicator surveys on Bioko Island: high association between urban communities and low-density infections
The study highlights the limitations of HRP2-based RDTs in detecting low density infections and underscores the potential of molecular tools like PlasmoPod in malaria surveillance. By identifying elusive transmission reservoirs and tracking parasite importation, molecular monitoring can play a crucial role in achieving malaria elimination. The findings advocate for the broader implementation of molecular diagnostics in malaria programs, especially in areas with low transmission, to enhance the detection and targeting of hidden reservoirs of infection.
Authors
- Joana C. Silva (ORCID: https://orcid.org/0000-0001-6502-7026)
- Elizabeth Nyakarungu
- José Raso Bijeri
- Carlos A. Guerra (ORCID: https://orcid.org/0000-0002-4069-9528)
- David S. Galick (ORCID: https://orcid.org/0009-0001-3028-7650)
- Tobias Schindler (ORCID: https://orcid.org/0000-0002-5961-095X)
- Salome Hosch (ORCID: https://orcid.org/0000-0001-9290-3589)
- Guillermo A. García (ORCID: https://orcid.org/0000-0002-4430-4781)
- Matilde Riloha Rivas
- Thomas C. Stabler
- Claudia Daubenberger (ORCID: https://orcid.org/0000-0001-7136-0642)
- Wonder P. Phiri
- Alejandro Lopelo Bolopá
- Johanna Nouria Giger
- Rosa Maria Oko Bedoung
- Esperanza Willy Roka
- Ana Gertrudis Nguema
- Victoria Palacios Ichinda
- Salvador Bakale
- Cristina Nka Esokolete
- Luca Montemartini
- Monserrat Kobe Elonga
- Rosalia Nzang Bibang
- Victoria Mangue Ndong
- Ilda Elobe Mometolo
Institutions
- University of Maryland, Baltimore (US)
- Swiss Tropical and Public Health Institute (CH)
- University of Basel (CH)
- Instituto de Medicina Tropical (PY)
- Medical Care Development International (US)
- National University of Equatorial Guinea (GQ)
- McKinsey & Company (United States) (US)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1186/s12936-025-05374-x
- Citations
- 3
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Universität Basel