Assessing the genetic profile of cytochrome P450 and glutathione S-transferases of patients diagnosed with acute myeloid leukemia

The study demonstrated that CYP450 and GST genes are polymorphic, and these polymorphisms may lead to longer neutrophilic recovery after induction treatment of acute myeloid leukemia remission.

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Publication Details

Journal
Hematology Transfusion and Cell Therapy
Published
2025-04-01
DOI
https://doi.org/10.1016/j.htct.2025.103759
Primary Topic
Glutathione Transferases and Polymorphisms
Type
article
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article

Assessing the genetic profile of cytochrome P450 and glutathione S-transferases of patients diagnosed with acute myeloid leukemia

Israel Bendit, Otávio César Carvalho Guimarães Baiocchi, Thiago Pagliarini, Eduardo Magalhães Rego et al.
Hematology Transfusion and Cell Therapy
Glutathione Transferases and Polymorphisms
article

Assessing the genetic profile of cytochrome P450 and glutathione S-transferases of patients diagnosed with acute myeloid leukemia

Israel Bendit, Otávio César Carvalho Guimarães Baiocchi, Thiago Pagliarini, Eduardo Magalhães Rego, Gilmar de Andrade França, Wellington Fernandes da Silva, Elvira Deolinda Rodrigues Pereira Velloso, Ricardo Rodrigues Giorgi, Luciana Nardinelli
article en

Abstract

The study demonstrated that CYP450 and GST genes are polymorphic, and these polymorphisms may lead to longer neutrophilic recovery after induction treatment of acute myeloid leukemia remission.

Hematology Transfusion and Cell TherapyVol. 47(2)
Hospital Alemão Oswaldo Cruz (BR), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 91%
Glutathione Transferases and Polymorphisms
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