Clozapine-induced Hypertensive & Tachycardia Twirls in a Schizophrenia Patient
The effectiveness of clozapine, a second-generation antipsychotic, in treating schizophrenia that is resistant to treatment is well established. Rare adverse effects like tachycardia and hypertension, however, might also result from it. In this case study, a 30-year-old woman with schizophrenia experienced tachycardia and chronic hypertension following clozapine medication. The patient’s heart rate and blood pressure were continuously raised, even though routine blood tests were within normal ranges. Eventually, atenolol was introduced to control these adverse effects. Although the precise mechanism by which clozapine causes tachycardia and hypertension is yet unknown, it is thought to be related to its alpha-adrenergic blocking capabilities and possible interactions with the D4 receptor. This case emphasises how crucial it is to start clozapine therapy with patients under strict observation for these unusual adverse effects
Authors
- Chayan Kanti Manna (ORCID: https://orcid.org/0000-0001-8132-4805)
- Moumita Mandal (ORCID: https://orcid.org/0000-0002-4751-2367)
Institutions
- ICARE Institute of Medical Sciences and Research & Dr. Bidhan Chandra Roy Hospital (IN)
Publication Details
- Journal
- Academic Bulletin of Mental Health
- Published
- 2025-05-07
- DOI
- https://doi.org/10.25259/abmh_2_2025
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00