Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL (Adv. Mater. Interfaces 9/2025)
Neural Device Development In article 2401001, Danesh Ashouri Vajari, Thomas Stieglitz, and co-workers investigate the impact of brain movement on the biocompatibility of neural probes by simulating strain profiles at the electrode-tissue interface under various displacements. Their findings challenge the 5% strain damage threshold, highlighting size-dependent micromotion models and the potential for integrating immunohistological data to assess probe design in the early stages of neural device development.
Authors
- Ali Sharbatian (ORCID: https://orcid.org/0000-0001-9531-4026)
- Danesh Ashouri Vajari (ORCID: https://orcid.org/0000-0002-6206-6756)
- Thomas C. Stieglitz (ORCID: https://orcid.org/0000-0002-7349-4254)
- Akhilesh Kamtikar
Institutions
- University of Freiburg (DE)
- Bernstein Center for Computational Neuroscience Freiburg (DE)
- Brain (Germany) (DE)
Publication Details
- Journal
- Advanced Materials Interfaces
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1002/admi.202570029
- Primary Topic
- Advanced Machining and Optimization Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00