Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL (Adv. Mater. Interfaces 9/2025)

Neural Device Development In article 2401001, Danesh Ashouri Vajari, Thomas Stieglitz, and co-workers investigate the impact of brain movement on the biocompatibility of neural probes by simulating strain profiles at the electrode-tissue interface under various displacements. Their findings challenge the 5% strain damage threshold, highlighting size-dependent micromotion models and the potential for integrating immunohistological data to assess probe design in the early stages of neural device development.

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Publication Details

Journal
Advanced Materials Interfaces
Published
2025-05-01
DOI
https://doi.org/10.1002/admi.202570029
Primary Topic
Advanced Machining and Optimization Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL (Adv. Mater. Interfaces 9/2025)

Ali Sharbatian, Danesh Ashouri Vajari, Thomas C. Stieglitz, Akhilesh Kamtikar
Advanced Materials Interfaces
Advanced Machining and Optimization Techniques
article

Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL (Adv. Mater. Interfaces 9/2025)

Ali Sharbatian, Danesh Ashouri Vajari, Thomas C. Stieglitz, Akhilesh Kamtikar
article en

Abstract

Neural Device Development In article 2401001, Danesh Ashouri Vajari, Thomas Stieglitz, and co-workers investigate the impact of brain movement on the biocompatibility of neural probes by simulating strain profiles at the electrode-tissue interface under various displacements. Their findings challenge the 5% strain damage threshold, highlighting size-dependent micromotion models and the potential for integrating immunohistological data to assess probe design in the early stages of neural device development.

Advanced Materials InterfacesVol. 12(9)
University of Freiburg (DE), Bernstein Center for Computational Neuroscience Freiburg (DE), Brain (Germany) (DE)
Openalex Percentile: Top 92%
Advanced Machining and Optimization Techniques
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