Short stature in pre-pubertal children with X-linked hypophosphatemia

In pre-pubertal children with XLH, a higher height Z score has associations with females, early initiation of treatment, better bone mineralization, and milder rachitic lesions. Conventional therapy improves their heights, but the efficacy does not depend on sex, active vitamin D dosage, or variant type.

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Publication Details

Journal
Endocrine Connections
Published
2025-05-07
DOI
https://doi.org/10.1530/ec-24-0605
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Short stature in pre-pubertal children with X-linked hypophosphatemia

Weibo Xia, Jiajun Zhao, Xiaoping Xing, Xiaosen Ma et al.
Endocrine Connections
Parathyroid Disorders and Treatments
article

Short stature in pre-pubertal children with X-linked hypophosphatemia

Weibo Xia, Jiajun Zhao, Xiaoping Xing, Xiaosen Ma, Ruizhi Jiajue, Hanting Liang, Yushuo Wu, Mei Li, Wei Liu, Chenxi Jin, Wenting Qi, Yue Chi, Yan Jiang, Qianqian Pang, Cong Zhang, Ou Wang
article en

Abstract

In pre-pubertal children with XLH, a higher height Z score has associations with females, early initiation of treatment, better bone mineralization, and milder rachitic lesions. Conventional therapy improves their heights, but the efficacy does not depend on sex, active vitamin D dosage, or variant type.

Endocrine ConnectionsVol. 14(6)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), China-Japan Friendship Hospital (CN), Peking Union Medical College Hospital (CN), Shandong Provincial Hospital (CN), Beijing Tsinghua Chang Gung Hospital (CN), Second Affiliated Hospital of Zhejiang University (CN), Shandong First Medical University (CN), Tsinghua University (CN)
National Natural Science Foundation of China, Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Peking Union Medical College
Good health and well-being
Openalex Percentile: Top 89%
Parathyroid Disorders and Treatments
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Short stature in pre-pubertal children with X-linked hypophosphatemia — Weibo Xia, Jiajun Zhao, et al. · Endocrine Connections (2025) | TGRS Research Map | TGRS