Significant Association Among the Epigenetic Alterations in <i>EGFR</i> and <i>ALK</i> Genes and Non–Small Cell Lung Cancer: A Prospective Emerging Molecular Biomarker
We analyzed methylation changes of EGFR and ALK genes in patients suffering from NSCLC. Alteration of EGFR gene methylation pattern could play an important role in the pathogenesis of NSCLC. To delineate the potential role of ALK somatic alterations, further investigations are warranted.
Authors
- Fatemeh Sadri (ORCID: https://orcid.org/0000-0003-4240-4217)
- Azim Nejatizadeh (ORCID: https://orcid.org/0000-0001-6347-0163)
- Mohsen Alipour (ORCID: https://orcid.org/0000-0003-4935-8487)
Institutions
- Hormozgan University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Annals of Human Genetics
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1111/ahg.12597
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00