Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or chronic care categories. Data were analysed by age, sex, and socio-demographic index, presenting total numbers and contributions to burden metrics such as Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLD), and Years of Life Lost (YLL). Approximately 68% of DALYs were attributed to chronic care, while 27% were due to acute care. Chronic care needs increased with age, representing 86% of YLDs and 71% of YLLs, and accounting for 93% of YLDs from sequelae. These findings highlight that chronic care needs far exceed acute care needs globally, necessitating health systems to adapt accordingly.

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Nature Communications
Published
2025-05-07
DOI
https://doi.org/10.1038/s41467-025-56910-x
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19
Primary Topic
Chronic Disease Management Strategies
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article
Field-Weighted Citation Impact
25.73

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article

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Steffan Wittrup Christensen
19 citations
Nature Communications
Chronic Disease Management Strategies
25.73
article

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Steffan Wittrup Christensen
article en
19 citations

Abstract

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or chronic care categories. Data were analysed by age, sex, and socio-demographic index, presenting total numbers and contributions to burden metrics such as Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLD), and Years of Life Lost (YLL). Approximately 68% of DALYs were attributed to chronic care, while 27% were due to acute care. Chronic care needs increased with age, representing 86% of YLDs and 71% of YLLs, and accounting for 93% of YLDs from sequelae. These findings highlight that chronic care needs far exceed acute care needs globally, necessitating health systems to adapt accordingly.

Nature CommunicationsVol. 16(1)
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Jahrom University of Medical Sciences (IR), Institute of Agricultural and Food Biotechnology (PL), Institute of Biophysics (RU), The George Institute for Global Health (AU), Federal Medical Centre (NG), Ministry of Health and Medical Education (IR), Bangladesh University of Health Sciences (BD), Children's Medical Center (IR), University of the Coast (CO), Slagelse Hospital (DK), CUF Porto Hospital (PT), York University (US), IRCCS Ospedale Galeazzi - Sant'Ambrogio (IT), Integrity Systems (United States) (US), Ospedale “M. 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Pascale" (IT), Peking University Third Hospital (CN), Torrens University Australia (AU), Health Data Research UK (GB), San Francisco VA Health Care System (US), Taylor's University (MY), Holy Family Hospital (GH), Micronesia Conservation Trust (FM), Perron Institute for Neurological and Translational Science (AU), Duke University Health System (US), Region Skåne (SE), Ospedale Policlinico San Martino (IT), Nottingham Biomedical Research Centre (GB), International Center for Tropical Agriculture (VN), South Eastern Sydney Local Health District (AU), National Center of Cardiology and Internal Medicine (KG), Oklahoma State University at Tulsa (US), Quest International University Perak (MY), École nationale supérieure de techniques avancées Bretagne (FR), Ministry of Health and Family Welfare (IN), Hospital de Santa Maria (PT), Jos University Teaching Hospital (NG), China Population and Development Research Center (CN), Hungarian Institute of Occupational Health (HU), Melbourne Clinic (AU), National University Health System (SG), Murdoch Children's Research Institute (AU), The Maria Sklodowska-Curie National Research Institute of Oncology (PL), Boston Children's Museum (US), Directorate General of Health Services (BD), Osaka International Cancer Institute (JP), French Community of Belgium (BE), Biocom (US), Aminu Kano Teaching Hospital (NG), Department of Veterans Affairs (AU), Koforidua Technical University (GH), Federal Institute for Population Research (DE), Institut Pasteur du Maroc (MA), Ospedale San Bortolo (IT), Shahid Motahari Hospital (IR), Istituti di Ricovero e Cura a Carattere Scientifico (IT), ARC Centre of Excellence for Children and Families over the Life Course (AU), D.Y. 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Blumberg Institute (US), Indonesian Orthopaedic Association (ID), i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT), Research Center of Neurology (RU), Ministry of Health and Population (EG), Ministry of Health and Social Welfare (GM), Yonsei University Health System (KR), Abt Associates (Nepal) (NP), Fasa University of Medical Sciences (IR), Statisticon (Sweden) (SE), Federal Teaching Hospital Abakaliki (NG), Institute of Child and Mother Health (BD), NIHR Birmingham Biomedical Research Centre (GB), City of Knowledge (PA), IRCCS Humanitas Research Hospital (IT), Ministry of Health (BH), Sinhgad Dental College and Hospital (IN), Medical Research Network (US), Act Health (AU), South Western Sydney Local Health District (AU), INCLEN Trust International (IN), National Institute of Health (PK), TissuPath (AU), Suraj Eye Institute (IN), Government Medical College (IN), Fondazione IRCCS Istituto Neurologico Carlo Besta (IT), National Institute for Medical Research (TZ), Beijing Advanced Sciences and Innovation Center (CN), October 6 University (EG), Network Group (Czechia) (CZ), Institute of Molecular and Clinical Ophthalmology Basel (CH), Urho Kaleva Kekkonen Institute (FI), Queen Elizabeth Hospital (CN), Community Health Alliance (US), Arba Minch University (ET), Health Services Academy (PK), Alborz University of Medical Sciences (IR), Kasturba Medical College, Mangalore (IN), University of Environment and Sustainable Development, National Research and Innovation Agency (ID), Lumbini Medical College, University of Medical Sciences, Ondo, HUTECH University, Sapientia Hungarian University of Transylvania (RO), Division of Cancer Epidemiology and Genetics, Urmia University of Medical Sciences (IR), Salale University, Berekum College of Education, Arsi University, All India Institute of Medical Sciences, Nagpur (IN), Varastegan Institute for Medical Sciences, Faculté de médecine de Tunis, Center for Water Quality Research, Non-Communicable Diseases Research Center, University of Bergen (NO), Kursk State Medical University (RU), University of Houston (US), Czech Technical University in Prague (CZ), University College London (GB), Addis Ababa University (ET), Technische Universität Berlin (DE), A.T. Still University (US), Jahangirnagar University (BD), Salahaddin University-Erbil (IQ), University of Manitoba (CA), King Faisal University (SA), Ho Chi Minh City University of Technology (VN), Imperial College London (GB), Taipei Medical University (TW), Mulawarman University (ID), Sultan Qaboos University (OM), Kathmandu University (NP), University of Oklahoma Health Sciences Center (US), Nigerian Institute of Medical Research (NG), Hamad Medical Corporation (QA), Rush University (US), McGill University (CA), University of Education (PK), Anglia Ruskin University (GB), Institute of Medical Sciences (IN), Panjab University (IN), University of Lincoln (GB), University of Colorado Anschutz Medical Campus (US), Keimyung University (KR), The Ohio State University (US), Rhode Island College (US), Arabian Gulf University (BH), National Institute of Nutrition (IN), Abasyn University (PK), University of Rochester (US), Sam Ratulangi University (ID), The University of Texas Medical Branch at Galveston (US), Arizona State University (US), University of Tartu (EE), Monash University (AU), University of Technology, Mauritius (MU), The University of Adelaide (AU), Bahir Dar University (ET), New York University (US), University of the Philippines Manila (PH), Shahid Beheshti University of Medical Sciences (IR), Southern Medical University (CN), Seattle University (US), Sofia University "St. Kliment Ohridski" (BG), Case Western Reserve University (US), St. Joseph’s Healthcare Hamilton (CA), Nagoya University (JP), University of Duhok (IQ), Qatar University (QA), University of Regensburg (DE), Qom University of Medical Science and Health Services (IR), University of Agriculture Faisalabad (PK), Jawaharlal Institute of Post Graduate Medical Education and Research (IN), Jackson State University (US), IMU University (MY), Geneva College (US), Morehouse School of Medicine (US), Western Sydney University (AU), Tunis El Manar University (TN), Universidad Autónoma de Madrid (ES), All India Institute of Medical Sciences (IN), University of Benin (NG), Qazvin University of Medical Sciences (IR), University of Sulaimani (IQ), Kobe University (JP), Naresuan University (TH), University of Milano-Bicocca (IT), Southern Cross University (AU), Universidade Federal de Goiás (BR), Indian Institute of Technology Delhi (IN), University of Pretoria (ZA), Hull York Medical School (GB), National Institute of Mental Health and Neurosciences (IN), Tehran University of Medical Sciences (IR), Utkal University (IN), Babol University of Medical Sciences (IR), Université de Montréal (CA), University of Reading (GB), University of Naples Federico II (IT), Sheffield Hallam University (GB), Shahroud University of Medical Sciences (IR), King Abdullah University of Science and Technology (SA), Universitat de Barcelona (ES), Makerere University (UG), Washington State University (US), Athens University of Economics and Business (GR), Coventry University (GB), Chitkara University (IN), University of Windsor (CA), Rajarata University of Sri Lanka (LK), Public Health Foundation of India (IN), Rice University (US), The University of Tokyo (JP), Mekelle University (ET), Gdańsk Medical University (PL), National Yunlin University of Science and Technology (TW), Zhejiang University (CN), Kharkiv National Medical University (UA), Kasturba Medical College, Manipal (IN), Hamilton Health Sciences (CA), Southeast University (CN), Imam Abdulrahman Bin Faisal University (SA), University of San Francisco (US), Icesi University (CO), University of Coimbra (PT), Aksum University (ET), Columbia University (US), University of Arkansas at Fayetteville (US), University of Newcastle Australia (AU), Charité - Universitätsmedizin Berlin (DE), United Nations Population Fund (US), University of Birmingham (GB), University of Arkansas for Medical Sciences (US), Pomeranian Medical University (PL), University of Veterinary and Animal Sciences (PK), Walden University (US), University of Otago (NZ), Universidade Federal de Uberlândia (BR), Ludwig-Maximilians-Universität München (DE), Agency for Healthcare Research and Quality (US), Universidade Nova de Lisboa (PT), University of Genoa (IT), Polytechnic Institute of Porto (PT), Alexandria University (EG), Sungkyunkwan University (KR), Saveetha University (IN), Yarmouk University (JO), Virginia Tech (US), Sapienza University of Rome (IT), James Cook University (AU), Australian Catholic University (AU), University of Oklahoma (US), Rafsanjan University of Medical Sciences (IR), University of the Western Cape (ZA), University of Tulsa (US), Xi'an Jiaotong University (CN), University of Management and Technology (PK), University of Gondar (ET), Savitribai Phule Pune University (IN), Mazandaran University of Medical Sciences (IR), University of Gothenburg (SE), Bucharest University of Economic Studies (RO), National University of Malaysia (MY), Marshall University (US), University of Amsterdam (NL), University of Hong Kong (HK), National Patient Safety Foundation (US), Aalborg University (DK), American University of Antigua (AG), Universidad Nacional Autónoma de México (MX), Yokohama City University (JP), Umeå University (SE), University of Rajshahi (BD), Medical Research Council (GB), Olusegun Agagu University of Science and Technology (NG), University of Colombo (LK), Kosin University (KR), London School of Economics and Political Science (GB), Zayed University (AE), Texas A&M University (US), University of Sheffield (GB), University of Haifa (IL), Banaras Hindu University (IN), Jazan University (SA), Debre Markos University (ET), Universidad de Colima (MX), Padjadjaran University (ID), The University of Texas Health Science Center at Houston (US), Bayero University Kano (NG), University of Colorado Denver (US), Ziauddin University (PK), Bournemouth University (GB), University of Bologna (IT), Ottawa University (US), Florida College (US), University of KwaZulu-Natal (ZA), University of California, Berkeley (US), Gazi University (TR), Birjand University of Medical Sciences (IR), National Yang Ming Chiao Tung University (TW), Dhaka Medical College and Hospital (BD), Stanford University (US), University of Lausanne (CH), McMaster University (CA), The University of Osaka (JP), University of Oulu (FI), American University of Beirut (LB), University of Edinburgh (GB), Icahn School of Medicine at Mount Sinai (US), Macquarie University (AU), Tsinghua University (CN), University of Gujrat (PK), KU Leuven (BE), University of Minho (PT)
U.S. Department of Veterans Affairs, Amgen, Eli Lilly and Company, Pfizer, AstraZeneca, Sanofi, Alexander von Humboldt-Stiftung, Alexion Pharmaceuticals, Emory University, University of Central Florida, HCF Research Foundation, Case Western Reserve University, Auckland University of Technology, New Zealand, University of Otago, International Parkinson and Movement Disorder Society, McGill University, Jazan University, London School of Hygiene and Tropical Medicine, Regeneron Pharmaceuticals, Wellcome Trust, Institute for Health Metrics and Evaluation, Fresenius Medical Care North America, Mylan, University of Engineering and Technology, Lahore, Trường Đại học Duy Tân, Rafsanjan University of Medical Sciences, SRM Institute of Science and Technology, Jawaharlal Nehru University, Asian Institute of Medicine, Science and Technology, Kasturba Medical College, Manipal, Neyshabur University of Medical Sciences, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Shaheed Benazir Bhutto University, University of Alberta, National Institute for Health and Care Research, Imperial College London, King's College London, University College London, European Commission, Arthritis Australia, Macquarie University, University of Tasmania, South African Medical Research Council, University of Pretoria, Department of Biotechnology, Ministry of Science and Technology, India, Department of Science and Technology, Ministry of Science and Technology, India, Indian Council of Medical Research, Charles Sturt University, University of New South Wales, University of Sydney, Deakin University, RMIT University, Academy of Scientific Research and Technology, Ain Shams University, Taibah University, Pohang University of Science and Technology, Banaras Hindu University, Science and Technology Development Fund, Ministero della Salute, Isfahan University of Medical Sciences, King Abdulaziz University, Tsinghua University, Shiraz University of Medical Sciences, Universiteit Stellenbosch, Tehran University of Medical Sciences and Health Services, Taipei Medical University, Chinese University of Hong Kong, Shahrekord University, Nankai University, Asia University, Shiraz University, Kermanshah University of Medical Sciences, Guilan University of Medical Sciences, Università degli Studi di Sassari, Shahrekord University of Medical Sciences, Göteborgs Universitet, Ateneo de Manila University, University of Dhaka, University of Tsukuba, Lung Foundation Australia, Federation University Australia, Secretaría Nacional de Ciencia, Tecnología e Innovación, China Medical University, Universidade Federal de Minas Gerais, Shaqra University, Indian Institute of Technology Delhi, Institute for Advanced Studies in Basic Sciences, University of Agriculture, Faisalabad, Universitatea de Medicină şi Farmacie "Carol Davila" Bucureşti, Khulna University, The Wellcome Trust DBT India Alliance, Charotar University of Science and Technology, Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu, Masarykova Univerzita, I.M. Sechenov First Moscow State Medical University, Applied Molecular Biosciences Unit, National Institute for Research in Tuberculosis, Cabrini Foundation, Idorsia Pharmaceuticals, Western Sydney University, Madda Walabu University, National Institutes of Health, Directorate for Biological Sciences, Directorate for Mathematical and Physical Sciences, Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Medical Research Council, National Health and Medical Research Council, Science and Engineering Research Board, Fundação para a Ciência e a Tecnologia, Sydney Medical School, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Biotechnology Industry Research Assistance Council, National Human Genome Research Institute, Division of Mathematical Sciences
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