Association of childhood-to-adulthood body size change with cancer risk: UK Biobank prospective cohort
While larger body size in childhood predisposes individuals to overweight and obesity in adulthood, maintaining a healthy weight in adulthood may help mitigate the risk of obesity-related cancers. Our findings highlight the importance of preventing and reducing overweight and obesity in adulthood for primary cancer prevention.
Authors
- Ben Schöttker (ORCID: https://orcid.org/0000-0002-1217-4521)
- Marko Mandic (ORCID: https://orcid.org/0000-0002-7372-8284)
- Fatemeh Safizadeh (ORCID: https://orcid.org/0000-0002-3293-9499)
- Michael Hoffmeister (ORCID: https://orcid.org/0000-0002-8307-3197)
- Hermann Brenner (ORCID: https://orcid.org/0000-0002-6129-1572)
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1186/s12916-025-04052-8
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- Cancer Research UK
- National Institute for Health and Care Research
- British Heart Foundation
- Diabetes UK
- Northwest Regional Development Agency
- Medical Research Council