Synthesis of 4-Chloro-2,6-bis(1H-imidazol-2-yl)pyridine

Chelidamic acid was successively converted to 4-chloropyridine-2,6-dicarboxamide and 4-chloro­pyridine-2,6-dicarbonitrile, and reaction of the latter with 2-aminoacetaldehyde diethyl acetal afforded 4-chloro-2,6-bis(1H-imidazol-2-yl)pyridine which is a promising tridentate ligand.

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Publication Details

Journal
Russian Journal of Organic Chemistry
Published
2025-03-01
DOI
https://doi.org/10.1134/s1070428024604801
Primary Topic
Synthesis and Reactions of Organic Compounds
Type
article
Field-Weighted Citation Impact
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article

Synthesis of 4-Chloro-2,6-bis(1H-imidazol-2-yl)pyridine

А. Ya. Tikhonov, I. A. Os’kina, Л. Г. Лавренова
Russian Journal of Organic Chemistry
Synthesis and Reactions of Organic Compounds
article

Synthesis of 4-Chloro-2,6-bis(1H-imidazol-2-yl)pyridine

А. Ya. Tikhonov, I. A. Os’kina, Л. Г. Лавренова
article en

Abstract

Chelidamic acid was successively converted to 4-chloropyridine-2,6-dicarboxamide and 4-chloro­pyridine-2,6-dicarbonitrile, and reaction of the latter with 2-aminoacetaldehyde diethyl acetal afforded 4-chloro-2,6-bis(1H-imidazol-2-yl)pyridine which is a promising tridentate ligand.

Russian Journal of Organic ChemistryVol. 61(3)
Novosibirsk Institute of Organic Chemistry (RU), Nikolaev Institute of Inorganic Chemistry (RU)
Openalex Percentile: Top 93%
Synthesis and Reactions of Organic Compounds
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