Synthesis of a Hexasubstituted Benzene Derivative from Pyridine-4-carbaldehyde and Malononitrile
Previously unknown 2-amino-4,6-di(pyridin-4-yl)benzene-1.3.5-tricarbonitrile has been synthesized by the 2:1 condensation of 2-(pyridin-4-ylmethylidene)malononitrile with malononitrile in the presence of N-methylpiperazine as catalyst. The product structure has been determined by NMR spectroscopy and X-ray analysis, and a probable mechanism of its formation has been proposed.
Authors
- Victor N. Khrustalev (ORCID: https://orcid.org/0000-0001-8806-2975)
- I. G. Mamedov
- Farid N. Naghiyev (ORCID: https://orcid.org/0009-0003-9325-1756)
- Ilya A. Yakushev (ORCID: https://orcid.org/0000-0001-6784-947X)
Institutions
- Peoples' Friendship University of Russia (RU)
- Baku State University (AZ)
- N.D. Zelinsky Institute of Organic Chemistry (RU)
- NS Kurnakova Institute of General and Inorganic Chemistry (RU)
Publication Details
- Journal
- Russian Journal of Organic Chemistry
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1134/s1070428024604473
- Citations
- 1
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.94