Identification and characterization of a novel human adenovirus type HAdV-D116
The unique genomic features of HAdV-D116, combined with the patient's immunodeficiency, are proposed to contribute to its possible CNS infectivity. The discovery of HAdV-D116 expands our understanding of human adenovirus tropism and underscores the need for vigilance regarding the emergence of novel adenovirus-related CNS infections.
Authors
- Dong Zhang (ORCID: https://orcid.org/0000-0003-3468-2639)
- Minya Lu
- Mange Liu
- Jiayu Guo
- Yi Qin Gao (ORCID: https://orcid.org/0000-0002-4309-9376)
- Shicheng Ma (ORCID: https://orcid.org/0009-0006-1316-9587)
- Xiang Ren (ORCID: https://orcid.org/0000-0001-5020-5838)
- Menglan Zhou (ORCID: https://orcid.org/0000-0003-1241-6153)
- Ying Zhao (ORCID: https://orcid.org/0000-0003-2366-0362)
- Yingchun Xu (ORCID: https://orcid.org/0000-0002-6534-9647)
- Wenjing Chen (ORCID: https://orcid.org/0000-0002-9824-4809)
- Huiting Su
- Qiwen Yang (ORCID: https://orcid.org/0009-0006-0195-4342)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Vision Medicals (China) (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-05-07
- DOI
- https://doi.org/10.3389/fmicb.2025.1566316
- Citations
- 1
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Peking Union Medical College Hospital
- Peking Union Medical College
- National Science and Technology Major Project
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities