Effect of CYP3A4 inhibitor and induction on the pharmacokinetics and safety of FHND9041, a novel EGFR T790M inhibitor, in healthy Chinese

Authors

Jian Ping Gong (ORCID: https://orcid.org/0000-0003-2228-2750)
Huan Zhou (ORCID: https://orcid.org/0000-0002-9396-8787)
Chang Lu (ORCID: https://orcid.org/0009-0008-6107-6099)
Yunqiu Xie (ORCID: https://orcid.org/0000-0002-1583-6180)
Minghong Shang
R. Chen
Dongmei Cheng (ORCID: https://orcid.org/0000-0002-4638-0884)
Yongqiang Zhu

Institutions

Shenyang Pharmaceutical University (CN)
China Pharmaceutical University (CN)
Bengbu Medical College (CN)
Anhui University of Finance and Economics (CN)
The Second Affiliated Hospital of Bengbu Medical College (CN)

Publication Details

Journal: BMC Pharmacology and Toxicology
Published: 2025-05-07
DOI: https://doi.org/10.1186/s40360-025-00930-2
Primary Topic: Lung Cancer Treatments and Mutations
Type: article
Field-Weighted Citation Impact: 0.00

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article

Effect of CYP3A4 inhibitor and induction on the pharmacokinetics and safety of FHND9041, a novel EGFR T790M inhibitor, in healthy Chinese

Jian Ping Gong, Huan Zhou, Chang Lu, Yunqiu Xie et al.

May 7, 2025

1 links

BMC Pharmacology and Toxicology

Lung Cancer Treatments and Mutations

article

Effect of CYP3A4 inhibitor and induction on the pharmacokinetics and safety of FHND9041, a novel EGFR T790M inhibitor, in healthy Chinese

Jian Ping Gong, Huan Zhou, Chang Lu, Yunqiu Xie, Minghong Shang, R. Chen, Dongmei Cheng, Yongqiang Zhu

May 7, 2025article en

Abstract

No abstract available for this paper.

BMC Pharmacology and ToxicologyVol. 26(1)

Shenyang Pharmaceutical University (CN), China Pharmaceutical University (CN), Bengbu Medical College (CN), Anhui University of Finance and Economics (CN), The Second Affiliated Hospital of Bengbu Medical College (CN)

Zero hunger

Openalex Percentile: Top 85%

Lung Cancer Treatments and Mutations

DOI Open Access PDF OpenAlex

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Effect of CYP3A4 inhibitor and induction on the pharmacokinetics and safety of FHND9041, a novel EGFR T790M inhibitor, in healthy Chinese — Jian Ping Gong, Huan Zhou, et al. · BMC Pharmacology and Toxicology (2025) | TGRS Research Map | TGRS