LILRB1 enhances the progression of diffuse large B-cell lymphoma through the CREB-SORBS3 pathway
In this work, we revealed that LILRB1 was highly expressed in DLBCL cells and was negatively correlated with patient survival. Furthermore, we found that the LILRB1-CREB-SORBS3 pathway played a role in maintaining the proliferation of DLBCL cells. These data suggest that LILRB1 might be a potential target for the treatment of DLBCL.
Authors
- Zhuo Yu (ORCID: https://orcid.org/0009-0008-4199-0289)
- Junke Zheng (ORCID: https://orcid.org/0000-0002-7023-2400)
- Hanqing Zhao (ORCID: https://orcid.org/0000-0003-0327-3699)
- Liyuan Cao (ORCID: https://orcid.org/0000-0003-0794-3645)
- Lietao Weng
- Chiqi Chen (ORCID: https://orcid.org/0000-0001-7220-8212)
- Jin Yuan
- Xuanyi Zhou
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Tongren Hospital (CN)
Publication Details
- Journal
- Cellular Oncology
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1007/s13402-025-01060-x
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Science and Technology Commission of Shanghai Municipality
- Shanghai Jiao Tong University
- School of Medicine, Shanghai Jiao Tong University
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities