Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

There was no evidence supporting a diagnosis of NSUC in this cohort. The data inclusive of independent examinations and neuropathology strongly supported the presence of several neurodegenerative and non-neurodegenerative conditions. Unfounded concerns that a potentially fatal mystery disease, possibly induced by an environmental toxin, is causing the patients' neurological symptoms has been amplified in traditional and social media. Second, independent clinical evaluations are needed for any patient given a diagnosis of NSUC.

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Publication Details

Journal
JAMA Neurology
Published
2025-05-07
DOI
https://doi.org/10.1001/jamaneurol.2025.1718
Citations
1
Primary Topic
Neurological and metabolic disorders
Type
article
Field-Weighted Citation Impact
1.29
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article

Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

Anthony E. Lang, Sarah C. Lidstone, Gabriela S. Gilmour, Maria Carmela Tartaglia et al.
1 citations
JAMA Neurology
Neurological and metabolic disorders
1.29
article

Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

Anthony E. Lang, Sarah C. Lidstone, Gabriela S. Gilmour, Maria Carmela Tartaglia, Alex Medina Escobar, Gerard H. Jansen, Nathaniel Bendahan, Sylvia Gautreau, Molly Macdonald, Lorraine V. Kalia, Eslam Abdellah, Sarmad Al‐Shamaa, Annette Thebeau
article en
1 citations

Abstract

There was no evidence supporting a diagnosis of NSUC in this cohort. The data inclusive of independent examinations and neuropathology strongly supported the presence of several neurodegenerative and non-neurodegenerative conditions. Unfounded concerns that a potentially fatal mystery disease, possibly induced by an environmental toxin, is causing the patients' neurological symptoms has been amplified in traditional and social media. Second, independent clinical evaluations are needed for any patient given a diagnosis of NSUC.

JAMA NeurologyVol. 82(8)
University Health Network (CA), University of Ottawa (CA), University of Calgary (CA), University of Toronto (CA), Toronto Western Hospital (CA), Toronto Rehabilitation Institute (CA), Horizon Health Network (CA), Baycrest Hospital (CA), Hotchkiss Brain Institute (CA)
Good health and well-being
Openalex Percentile: Top 20%
Neurological and metabolic disorders
1.29
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Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause — Anthony E. Lang, Sarah C. Lidstone, et al. · JAMA Neurology (2025) | TGRS Research Map | TGRS