Osteodencytometric Diagnostics in Women with Oophorectomy

Abstract: Oophorectomy, particularly bilateral, is associated with a significant risk of bone mineral density (BMD) loss due to abrupt oestrogen deficiency. This study aimed to assess the effectiveness of osteodensitometric diagnostics in detecting early postoophorectomy bone demineralisation in women. A total of 62 women aged 35–60 years who had undergone unilateral or bilateral oophorectomy were evaluated using dual-energy X-ray absorptiometry (DEXA). The results showed that 45.2% had osteopenia and 24.2% had osteoporosis, with more severe BMD loss observed in those with bilateral oophorectomy and greater time elapsed since surgery. The lumbar spine showed the most significant decline. A negative correlation was found between BMD and both the time since oophorectomy and serum oestradiol levels. These findings highlight the importance of early DEXA screening and long-term monitoring in surgically menopausal women, particularly in those without hormone replacement therapy, to prevent osteoporosis and its complications