Onset and Resolution of Ocular Motor Cranial Nerve Palsies Following the Use of Intra-Arterial Chemotherapy for Retinoblastoma

Cranial nerve palsy is an infrequent occurrence after IAC but families need to be aware of this as a complication. It is reassuring that the majority resolve. In our experience, a high cumulative dose of melphalan due to the refractory nature of the tumour increases the risk of this complication long term.

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Publication Details

Journal
Seminars in Ophthalmology
Published
2025-05-07
DOI
https://doi.org/10.1080/08820538.2025.2501796
Citations
1
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
1.71
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article

Onset and Resolution of Ocular Motor Cranial Nerve Palsies Following the Use of Intra-Arterial Chemotherapy for Retinoblastoma

Mandeep S. Sagoo, M. Ashwin Reddy, Zishan Naeem, Ali Abdall-Razak et al.
1 citations
Seminars in Ophthalmology
Ocular Oncology and Treatments
1.71
article

Onset and Resolution of Ocular Motor Cranial Nerve Palsies Following the Use of Intra-Arterial Chemotherapy for Retinoblastoma

Mandeep S. Sagoo, M. Ashwin Reddy, Zishan Naeem, Ali Abdall-Razak, Fergus Robertson, Catriona Duncan
article en
1 citations

Abstract

Cranial nerve palsy is an infrequent occurrence after IAC but families need to be aware of this as a complication. It is reassuring that the majority resolve. In our experience, a high cumulative dose of melphalan due to the refractory nature of the tumour increases the risk of this complication long term.

Seminars in OphthalmologyVol. 40(6)
Moorfields Eye Hospital NHS Foundation Trust (GB), Queen Mary University of London (GB), Great Ormond Street Hospital (GB), Great Ormond Street Hospital for Children NHS Foundation Trust (GB), Royal London Hospital (GB), Moorfields Eye Hospital (GB), University College London (GB)
Good health and well-being
Openalex Percentile: Top 19%
Ocular Oncology and Treatments
1.71
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Onset and Resolution of Ocular Motor Cranial Nerve Palsies Following the Use of Intra-Arterial Chemotherapy for Retinoblastoma — Mandeep S. Sagoo, M. Ashwin Reddy, et al. · Seminars in Ophthalmology (2025) | TGRS Research Map | TGRS