An elevated percentage of CD4⁺CD25⁺CD127low regulatory T cells in peripheral blood indicates a poorer prognosis in hepatocellular carcinoma after curative hepatectomy
The percentage of CD4⁺CD25⁺ CD127<sup>low</sup> Tregs in peripheral blood is associated with poor prognosis in HCC patients. It can be suggested as a potential prognostic indicator for HCC patients after hepatectomy and complement existing risk stratification tools. Measuring the percentage of CD4⁺CD25⁺ CD127<sup>low</sup> Tregs may contribute to the formulation of treatment strategies and the improvement of the prognosis for HCC patients.
Authors
- Zhongbiao Chen (ORCID: https://orcid.org/0000-0003-2168-8898)
- Binyu Zhao (ORCID: https://orcid.org/0000-0002-1694-3367)
- Zhong Cao (ORCID: https://orcid.org/0009-0001-6262-3831)
- Bin Zhang (ORCID: https://orcid.org/0000-0001-7313-9300)
- Haoran Sun (ORCID: https://orcid.org/0009-0007-7817-1773)
- Dachen Zhou
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1186/s12876-025-03940-w
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Anhui Medical University