Predictive value of the RENAL nephrometry score on oncological and functional outcomes in cT1 renal cell carcinoma treated with cone-beam CT-guided percutaneous cryoablation

Abstract Stage 1 (cT1) renal cell carcinoma (RCC) can be treated by cone-beam CT-guided percutaneous cryoablation (CBCT-guided PCA). The RENAL nephrometry scoring system provides a structured method for evaluating the complexity of renal tumours by classifying them based on specific anatomical features. The aim was to evaluate the clinical utility of this scoring system in predicting postoperative oncological and functional outcomes in patients undergoing CBCT-guided PCA as their primary treatment for biopsy proven cT1 RCC. 91 patients were retrospectively analyzed. A statistically significant association was found between the RENAL nephrometry score classification and local treatment failure ( p = 0.005). The RENAL score was not found to correlate with local tumour recurrence, postoperative complications, or change in renal function. These findings suggest that the RENAL nephrometry score can be utilized for risk stratification and more precise patient counseling.