Spatial and Temporal Changes in Choroid Morphology Associated With Long-Duration Spaceflight
The findings suggest that localized choroid pulsatile changes occur following prolonged microgravity exposure. They show that the choroid vessels expand in a manner similar to the choroid layer across the macular region during spaceflight, with a relative increase in the space they occupy. The methods developed provide new tools and avenues for studying and establishing effective countermeasures to risks associated with long-duration spaceflight.
Authors
- Charles Bélanger Nzakimuena
- Rémy Marcotte-Collard (ORCID: https://orcid.org/0000-0001-9499-1287)
- Santiago Costantino (ORCID: https://orcid.org/0000-0002-2454-2635)
- Mark R. Lesk
- Marissé Masís Solano (ORCID: https://orcid.org/0000-0002-1055-669X)
Institutions
- Hôpital Maisonneuve-Rosemont (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1167/iovs.66.5.17
- Primary Topic
- Spaceflight effects on biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Aeronautics and Space Administration
- Université de Montréal
- Canadian Space Agency
- Canadian Institutes of Health Research