Fucoxanthin ameliorates Propionibacterium acnes-induced ear inflammation in mice by modulating the IκBα/NF-κB signaling pathway and inhibiting NF-κB nuclear translocation
Fucoxanthin exerts anti-acne effects through coordinated inhibition of IκBα degradation and NF-κB nuclear translocation, establishing its potential as a targeted therapeutic agent for inflammatory acne.
Authors
- Bingqi Dong (ORCID: https://orcid.org/0009-0006-9380-4092)
- Hu Mao (ORCID: https://orcid.org/0000-0003-2252-5572)
- Yan Chen (ORCID: https://orcid.org/0000-0002-7713-6913)
- Xiaoyan Peng (ORCID: https://orcid.org/0000-0002-4275-6856)
- Shan Jiang (ORCID: https://orcid.org/0000-0002-2968-5109)
Institutions
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1371/journal.pone.0322950
- Citations
- 2
- Primary Topic
- Acne and Rosacea Treatments and Effects
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Natural Science Foundation of Hubei Province