Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats
Our results suggest that ISF transport in the linea alba may serve as an important mechanistic pathway bridging acupuncture stimulation to ovarian regulation. Our study not only provides a mechanistic basis for the clinical efficacy of acupuncture in treating ovarian disorders but also identifies ISF dynamics as a novel therapeutic target in age-related ovarian dysfunction.
Authors
- Chenchen Su
- Huan-Fang Xu
- Pengfei Du (ORCID: https://orcid.org/0000-0002-1096-8125)
- Yigong Fang (ORCID: https://orcid.org/0000-0001-7879-2843)
- Shuyou Wang (ORCID: https://orcid.org/0000-0002-2456-0040)
- Weixin Li (ORCID: https://orcid.org/0000-0001-7478-0378)
- Li Yang (ORCID: https://orcid.org/0000-0002-5484-0895)
- Xiaojing Song (ORCID: https://orcid.org/0000-0002-2148-2956)
- Ge Lu (ORCID: https://orcid.org/0000-0002-4524-6018)
- Yaoyao Zhu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fendo.2025.1579031
- Citations
- 1
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- National Key Research and Development Program of China