HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction
These findings elucidate a novel mechanism where HIF-1α and TGF-β1 cooperatively regulate ECM production in pancreatic cancer, providing potential therapeutic targets for intervention.
Authors
- Linxun Liu (ORCID: https://orcid.org/0000-0003-1998-5746)
- Hui Guo (ORCID: https://orcid.org/0000-0002-9155-4150)
- Zhanxue Zhao
Institutions
- Soochow University (CN)
- Qinghai Provincial Peoples Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fonc.2025.1564655
- Citations
- 3
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 3.14