Case Report: A rare case of renal failure secondary to in utero megalourethra
Unlike previously described cases, this case is unique due to the patient's abrupt progression to anhydramnios at 34 weeks and 5 days, despite having normal amniotic fluid levels prior to that. With late-onset anhydramnios, the severity of renal dysfunction was unexpected. Proximal urethrostomy requires further assessment as a potential intervention to successfully bypass the megalourethra and prevent infection. Long-term management is expected to include dialysis as a bridge to transplantation. Multiple corrective urological surgeries will be required to repair the urethra and restore penile function. Timely prenatal diagnosis of megalourethra or renal anomalies is essential for predicting long-term prognosis, as these conditions can lead to significant postnatal complications.
Authors
- Chryso Katsoufis (ORCID: https://orcid.org/0000-0002-8872-1165)
- Carolyn Abitbol (ORCID: https://orcid.org/0000-0002-0984-3771)
- Rayan S. Terkawi (ORCID: https://orcid.org/0000-0001-9350-1004)
- Sana Barkat Ali
- Tania D. Fontánez-Nieves
- Rodrigo Ruano (ORCID: https://orcid.org/0000-0002-3642-5858)
- Joanne Duara (ORCID: https://orcid.org/0000-0003-0600-3299)
Institutions
- University of Miami Hospital (US)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fped.2025.1546561
- Primary Topic
- Ureteral procedures and complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00