Correlation Between Vitamin D Levels and Dyslipidemia in Patients at Fann University Hospital

Vitamin D has been recognized for several decades as an important player in bone metabolism. Beyond these classic effects on mineral metabolism, it has numerous extra-osseous effects, including effects on the cardiovascular system. Indeed, several clinical studies suggest a link between vitamin D deficiency and cardiovascular mortality. The general objective is to evaluate the relationship between vitamin D levels and lipid parameters in patients at Fann University Hospital. Included in this study were 214 patients who came to the laboratory and whose vitamin D dosage was requested between December 2023 and April 2024. Lipid profile parameter dosages were performed with the Architect Ci4100 and vitamin D with Iflash 3000. Correlations between vitamin D levels and blood lipids were assessed by descriptive statistical analysis and Spearman's correlation test. The mean age of our population was 60±17 years and the sex ratio was 0.51. The distribution of patients according to the lipid profile showed that 72.42% of the subjects had a lipid abnormality with a predominance of hypo HDL-cholesterolemia (39.71%). Our study showed a positive and significant correlation between low vitamin D levels and low HDL-cholesterol levels. In contrast, no strong link was found with the levels of total cholesterol, triglycerides and LDL-cholesterol. These results highlight the importance of monitoring vitamin D levels in patients with dyslipidemia, and pave the way for future research on the potential role of vitamin D in cardiovascular risk management.