Changes of intestinal microbiome and its relationship with painful diabetic neuropathy in rats
This study demonstrates that PDN leads to altered gut microbiota composition, disrupted metabolic pathways, and increased inflammation, contributing to the pathological progression of diabetic neuropathy. This study provides new insights into the interplay between gut microbiota and diabetic neuropathy, offering potential avenues for therapeutic interventions targeting microbiome and metabolism.
Authors
- Shuaiying Jia (ORCID: https://orcid.org/0009-0008-4260-3818)
- Zhi Ming
- Jingyan Lin (ORCID: https://orcid.org/0000-0001-6706-0751)
- Yuning Liu (ORCID: https://orcid.org/0000-0002-9441-9667)
- Su Yao (ORCID: https://orcid.org/0000-0001-9808-1184)
- Haiqi Mi
Institutions
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s12866-025-04015-2
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Bureau of Science and Technology Nanchong City