Serum aluminum in 176 feline patients with application to the diagnostic approach to a tremoring patient with kidney disease receiving aluminum hydroxide therapy
Our data suggest that serum aluminum concentrations in cats exceeding 86 ng/mL can result in clinical aluminum toxicosis and is comparable to the 100 ng/mL toxic threshold described in humans. The data provided facilitate the diagnostic assessment of cats receiving aluminum hydroxide supplementation. Veterinarians must recognize the toxic effects of aluminum and pursue diagnostic testing in suspect cases to mitigate invasive and costly workup for aluminum-associated clinical signs or euthanasia due to deterioration of these patients.
Authors
- John P. Buchweitz (ORCID: https://orcid.org/0000-0003-4077-5014)
- Birgit Puschner (ORCID: https://orcid.org/0000-0001-6765-5085)
- Sarah Rebolloso
- Rachel Sheffler
- Stephanie Karpf
- Vicki Miksicek
Institutions
- Palm Beach Neurology (US)
- Michigan State University (US)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s12917-025-04788-8
- Primary Topic
- Aluminum toxicity and tolerance in plants and animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Michigan State University
- College of Engineering, Michigan State University