First-in-human pilot study of snapshot multispectral endoscopy for delineation of pituitary adenoma
The MSI endoscope holds the potential to differentiate adenoma tissue and healthy pituitary. With further development, MSI endoscopy could enable real-time label-free delineation of tumors during surgery, based on quantitative thresholds, which should contribute to improving the completeness of resection, while helping to preserve the pituitary gland, preventing serious life-changing complications.
Authors
- James R. Tysome (ORCID: https://orcid.org/0000-0002-2483-8700)
- Dale J. Waterhouse (ORCID: https://orcid.org/0000-0001-5530-6857)
- Sarah E. Bohndiek (ORCID: https://orcid.org/0000-0003-0371-8635)
- Thomas Santarius (ORCID: https://orcid.org/0000-0002-1416-9566)
- Daniele Borsetto (ORCID: https://orcid.org/0000-0003-3464-2688)
Institutions
- University of Cambridge (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Addenbrooke's Hospital (GB)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1117/1.jbo.30.5.056002
- Citations
- 4
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.18
Funders
- UK Research and Innovation
- Cancer Research UK
- University of Cambridge
- Cambridge University Hospitals
- Engineering and Physical Sciences Research Council