Spatial transcriptional landscape of human heart failure

These findings highlight the critical role of cell-enriched and histology-specific transcriptome mapping in understanding the complex pathophysiological landscape of failing hearts, offering molecular insights and potential therapeutic targets for future interventions.

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Publication Details

Journal
European Heart Journal
Published
2025-05-07
DOI
https://doi.org/10.1093/eurheartj/ehaf272
Citations
7
Primary Topic
Cardiac Fibrosis and Remodeling
Type
article
Field-Weighted Citation Impact
9.72

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article

Spatial transcriptional landscape of human heart failure

Ali Torkamani, Shang‐Fu Chen, Jae‐Joong Kim, Hee Sang Hwang et al.
7 citations
European Heart Journal
Cardiac Fibrosis and Remodeling
9.72
article

Spatial transcriptional landscape of human heart failure

Ali Torkamani, Shang‐Fu Chen, Jae‐Joong Kim, Hee Sang Hwang, Sung‐Ho Jung, Kyoung Yul Lee, Jeong Seok Lee, Junho Hyun, Kyung‐Hee Kim, Sang Eun Lee, Min‐Seok Kim, J.–H. Joo, Douglas Evans
article en
7 citations

Abstract

These findings highlight the critical role of cell-enriched and histology-specific transcriptome mapping in understanding the complex pathophysiological landscape of failing hearts, offering molecular insights and potential therapeutic targets for future interventions.

European Heart JournalVol. 46(31)
Ulsan College (KR), Scripps Institution of Oceanography (US), Korea Advanced Institute of Science and Technology (KR), Asan Medical Center (KR), Torrey Pines Institute For Molecular Studies (US), University of Ulsan (KR), Scripps (United States) (US), Incheon Medical Center (KR)
Georgia Clinical and Translational Science Alliance, National Research Foundation, Korea Health Industry Development Institute, Asan Institute for Life Sciences, Asan Medical Center, Ministry of Science and ICT, South Korea, National Institutes of Health, National Center for Advancing Translational Sciences
Good health and well-being
Openalex Percentile: Top 2%
Cardiac Fibrosis and Remodeling
9.72
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Spatial transcriptional landscape of human heart failure — Ali Torkamani, Shang‐Fu Chen, et al. · European Heart Journal (2025) | TGRS Research Map | TGRS