Combination therapy for multidrug-resistant <i>Mycoplasma genitalium</i> infections: a case series
This case series demonstrates the potential efficacy of M3P as a novel salvage therapy for MDR <i>M. genitalium</i> urethritis, particularly where standard therapies have failed. The combination of pristinamycin, methenamine, and other agents may synergistically reduce bacterial load and increase efficacy. Further, in vitro and clinical studies are required to assess the optimal treatment strategies for MDR <i>M. genitalium</i>.
Authors
- Irith De Baetselier (ORCID: https://orcid.org/0000-0002-1804-252X)
- Jens Van Praet (ORCID: https://orcid.org/0000-0002-7125-7001)
- Diana Huis in ‘t Veld (ORCID: https://orcid.org/0000-0002-5806-4352)
- Dorien Van den Bossche (ORCID: https://orcid.org/0000-0002-7545-4360)
- Sheeba Santhini Manoharan-Basil (ORCID: https://orcid.org/0000-0001-8421-5137)
- Benjamin J Visser (ORCID: https://orcid.org/0000-0002-5409-9662)
- Thibaut Vanbaelen (ORCID: https://orcid.org/0000-0002-5541-6041)
- Chris Kenyon (ORCID: https://orcid.org/0000-0002-2557-8998)
Institutions
- University of Cape Town (ZA)
- Ghent University Hospital (BE)
- AZ Sint-Jan (BE)
- Instituut voor Tropische Geneeskunde (BE)
Publication Details
- Journal
- Sexually Transmitted Infections
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1136/sextrans-2025-056517
- Citations
- 3
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 3.55