High rates of post-tuberculosis lung disease among persons successfully treated for drug-susceptible and resistant tuberculosis
Using comprehensive criteria, we found nearly three in four individuals with microbial cure status for TB disease had prevalent PTLD regardless of drug resistance status. Persistent cavitary disease was associated with serum markers of inflammation and lung tissue remodelling.
Authors
- Matthew James Magee (ORCID: https://orcid.org/0000-0002-8068-5796)
- Sara C. Auld (ORCID: https://orcid.org/0000-0002-8972-3736)
- Arijita Subuddhi (ORCID: https://orcid.org/0000-0002-8777-9533)
- Zaza Avaliani (ORCID: https://orcid.org/0000-0002-8790-3282)
- Sergo A. Vashakidze (ORCID: https://orcid.org/0000-0001-5907-4870)
- Hardy Kornfeld (ORCID: https://orcid.org/0000-0002-8970-7306)
- Cheryl L. Day
- Nino A. Jakobia
- Russell Ryan Kempker (ORCID: https://orcid.org/0000-0002-7188-4996)
- Argita D. Salindri (ORCID: https://orcid.org/0000-0003-0962-0348)
- Teona Avaliani (ORCID: https://orcid.org/0000-0001-8587-7650)
- Adam Bernheim
- Cassandra Bryan
- Maia Kipiani (ORCID: https://orcid.org/0000-0002-5913-3858)
- Leila Goginashvili
- Krista N Krish
Institutions
- Queens College, CUNY (US)
- Emory University (US)
- University of Massachusetts Chan Medical School (US)
- Georgia State University (US)
- New York Hospital Queens (US)
- Queens Hospital Center (US)
- National Center for Tuberculosis and Lung Disease (GE)
- University of Georgia (GE)
- David Tvildiani Medical University (GE)
- Stanford University (US)
Publication Details
- Journal
- Thorax
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1136/thorax-2024-222350
- Citations
- 3
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- National Institute of Allergy and Infectious Diseases
- Fogarty International Center