Utilizing non-clonal CHO cell derived materials for preclinical studies of complex molecules
In conclusion, non-clonal CHO cell derived materials can be effectively utilized for preclinical studies of complex molecules without compromising their quality, allowing for accelerated development for FIH studies.
Authors
- Li GuangHua
- Ying Huang (ORCID: https://orcid.org/0000-0003-4606-6286)
- Katelyn Smith
- Alex Dow
- Daniel Burke (ORCID: https://orcid.org/0000-0003-0709-5164)
- Xiaowen Wang (ORCID: https://orcid.org/0009-0004-0801-8982)
- Simon Letarte (ORCID: https://orcid.org/0000-0001-9131-0327)
- Jeffrey T. McPhee
- K. Agarwal (ORCID: https://orcid.org/0000-0002-7872-6640)
- Balrina Gupta
- Jessica Pan (ORCID: https://orcid.org/0000-0002-8640-9768)
- Ren Liu (ORCID: https://orcid.org/0000-0001-8967-130X)
- Nuno Pinto (ORCID: https://orcid.org/0000-0002-9710-4353)
- Patricia Rose
Institutions
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
Publication Details
- Journal
- BMC Biotechnology
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1186/s12896-025-00968-4
- Citations
- 1
- Primary Topic
- Viral Infectious Diseases and Gene Expression in Insects
- Type
- article
- Field-Weighted Citation Impact
- 0.81