An optimized transformer model for efficient detection of thoracic diseases in chest X-rays with multi-scale feature fusion

This study presents the development and application of an optimized Detection Transformer (DETR) model, known as CD-DETR, for the detection of thoracic diseases from chest X-ray (CXR) images. The CD-DETR model addresses the challenges of detecting minor pathologies in CXRs, particularly in regions with uneven medical resource distribution. In the central and western regions of China, due to a shortage of radiologists, CXRs from township hospitals are concentrated in central hospitals for diagnosis. This requires processing a large number of CXRs in a short period of time to obtain results. The model integrates a multi-scale feature fusion approach, leveraging Efficient Channel Attention (ECA-Net) and Spatial Attention Upsampling (SAU) to enhance feature representation and improve detection accuracy. It also introduces a dedicated Chest Diseases Intersection over Union (CDIoU) loss function to optimize the detection of small targets and reduce class imbalance. Experimental results on the NIH Chest X-ray dataset demonstrate that CD-DETR achieves a precision of 88.3% and recall of 86.6%, outperforming other DETR variants by an average of 5% and CNN-based models like YOLOv7 by 6-8% in these metrics, showing its potential for practical application in medical imaging diagnostics.

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Publication Details

Journal
PLoS ONE
Published
2025-05-07
DOI
https://doi.org/10.1371/journal.pone.0323239
Citations
3
Primary Topic
COVID-19 diagnosis using AI
Type
article
Field-Weighted Citation Impact
4.08
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article

An optimized transformer model for efficient detection of thoracic diseases in chest X-rays with multi-scale feature fusion

Shasha Yu, Peng Zhou
3 citations
PLoS ONE
COVID-19 diagnosis using AI
4.08
article

An optimized transformer model for efficient detection of thoracic diseases in chest X-rays with multi-scale feature fusion

Shasha Yu, Peng Zhou
article en
3 citations

Abstract

This study presents the development and application of an optimized Detection Transformer (DETR) model, known as CD-DETR, for the detection of thoracic diseases from chest X-ray (CXR) images. The CD-DETR model addresses the challenges of detecting minor pathologies in CXRs, particularly in regions with uneven medical resource distribution. In the central and western regions of China, due to a shortage of radiologists, CXRs from township hospitals are concentrated in central hospitals for diagnosis. This requires processing a large number of CXRs in a short period of time to obtain results. The model integrates a multi-scale feature fusion approach, leveraging Efficient Channel Attention (ECA-Net) and Spatial Attention Upsampling (SAU) to enhance feature representation and improve detection accuracy. It also introduces a dedicated Chest Diseases Intersection over Union (CDIoU) loss function to optimize the detection of small targets and reduce class imbalance. Experimental results on the NIH Chest X-ray dataset demonstrate that CD-DETR achieves a precision of 88.3% and recall of 86.6%, outperforming other DETR variants by an average of 5% and CNN-based models like YOLOv7 by 6-8% in these metrics, showing its potential for practical application in medical imaging diagnostics.

PLoS ONEVol. 20(5)
Wuhan University (CN), Zhongnan Hospital of Wuhan University (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 7%
COVID-19 diagnosis using AI
4.08
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An optimized transformer model for efficient detection of thoracic diseases in chest X-rays with multi-scale feature fusion — Shasha Yu, Peng Zhou · PLoS ONE (2025) | TGRS Research Map | TGRS