Expression patterns, prognostic significance, and immune correlations of the TNFAIP8 family in acute myeloid leukemia: a comprehensive bioinformatics analysis
TNFAIP8 family genes play distinct roles in AML pathogenesis and immune regulation. TNFAIP8L2 shows promise as a prognostic biomarker, while TNFAIP8 and TNFAIP8L1 may indicate adverse cytogenetic risk. The study highlights their potential as therapeutic targets in AML.
Authors
- Xuezhong Zhang (ORCID: https://orcid.org/0000-0002-7159-4702)
- Lei Bi
- Tonggang Liu (ORCID: https://orcid.org/0000-0003-1550-8029)
- Xiaolei Wang (ORCID: https://orcid.org/0000-0002-6950-4309)
- Min Qu
Institutions
- Central Hospital of Zibo (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1007/s12672-025-02511-5
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80