[Clinical Characteristics and Prognostic Analysis of Childhood Acute Lymphoblastic Leukemia with Positive <i>E2A-PBX1</i> Fusion Gene].
In ALL children with positive <i>E2A-PBX1</i> fusion gene, those with elevated WBC counts and high risk stratification at initial diagnosis are more likely to experience recurrence. Recurrence is the main cause of death in this group. It is suggested that such kind of children receive more intensive chemotherapy or undergo hematopoietic stem cell transplantation as early as possible to further improve prognosis.
Authors
- Bo-Fei Hu (ORCID: https://orcid.org/0000-0002-8584-7424)
- Xiaojun Xu (ORCID: https://orcid.org/0000-0003-1388-2535)
- Jingying Zhang (ORCID: https://orcid.org/0009-0005-6130-2779)
- Weiqun Xu
- Yongmin Tang
- Ming Jia
Institutions
- Children's Hospital of Zhejiang University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2025.02.002
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article