[Analysis of the Influencing Factors of ABO Blood Group Antibody Origin and Titer in Neonates].

The majority of ABO blood group antibodies in neonates are IgG antibodies from the mothers, and few are produced by the neonates themselves. In some neonates, IgG anti-A and/or anti-B can agglutinate with anti-stereotyped cells at room temperature. The maternal ABO blood type is the primary factor influencing the titer of the newborn blood type. The number of maternal pregnancies is a factor affecting the high titer ABO blood group antibodies in newborns.

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Publication Details

Journal
PubMed
Published
2025-04-01
DOI
https://doi.org/10.19746/j.cnki.issn.1009-2137.2025.02.031
Primary Topic
Blood groups and transfusion
Type
article
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[Analysis of the Influencing Factors of ABO Blood Group Antibody Origin and Titer in Neonates].

Xiang Shi, Yu Zhou, Chun Yang, M. Yang et al.
PubMed
Blood groups and transfusion
article

[Analysis of the Influencing Factors of ABO Blood Group Antibody Origin and Titer in Neonates].

Xiang Shi, Yu Zhou, Chun Yang, M. Yang, Zhang Li
article en

Abstract

The majority of ABO blood group antibodies in neonates are IgG antibodies from the mothers, and few are produced by the neonates themselves. In some neonates, IgG anti-A and/or anti-B can agglutinate with anti-stereotyped cells at room temperature. The maternal ABO blood type is the primary factor influencing the titer of the newborn blood type. The number of maternal pregnancies is a factor affecting the high titer ABO blood group antibodies in newborns.

PubMedVol. 33(2)
Sichuan University (CN), West China Hospital of Sichuan University (CN), Chengdu Military General Hospital (CN)
Good health and well-being
Blood groups and transfusion
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