[Molecular Mechanism of Thymoquinone Inhibition on Malignant Proliferation of Acute Myeloid Leukemia Cells].
Thymoquinone can inhibit the proliferation of AML cells, and its mechanism may be related to inhibiting the activation of PI3K/Akt/mTOR signaling pathway, regulating the expression of apoptotic proteins and core members of SOX family.
Authors
- Yan-Quan Liu
- Fanlin Zeng (ORCID: https://orcid.org/0000-0002-7831-0071)
- Zhimin Yan (ORCID: https://orcid.org/0000-0002-0751-7374)
- Zhuoyu Li (ORCID: https://orcid.org/0009-0006-9858-6733)
- Hong-Quan Zhu
- Qinglin Xu (ORCID: https://orcid.org/0000-0001-8589-8646)
- Jie Lin
Institutions
- Guangdong Medical College (CN)
- Dongguan People’s Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2025.02.001
- Primary Topic
- Nigella sativa pharmacological applications
- Type
- article